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Received April 23, 2003; accepted Aug. 4, 2003. From the Department of Psychiatry and Human Behavior, Brown University School of Medicine, Rhode Island Hospital, Providence, R.I. This research was supported, in part, by grants MH48732 and MH56404 from the National Institute of Mental Health, Bethesda, Md. Corresponding author and reprints: Mark Zimmerman, M.D., Bayside Medical Center, 235 Plain Street, Providence, RI 02905 (e-mail: mzimmerman@lifespan.org). properties of the MDQ would suggest that the conclusions drawn from the epidemiologic study may not be justified. The purpose of the present commentary is to review principles of diagnostic screening and apply them to the studies of the MDQ. We begin by reviewing the goals and purposes of screening. Then, we review the statistics of diagnostic testing. Finally, we critically examine the performance of the MDQ.

Using Questionnaires to Screen for Psychiatric Disorders: A Comment on a Study of Screening for Bipolar Disorder in the Community