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Major depressive disorder (MDD) and posttraumatic stress disorder (PTSD) are commonly comorbid conditions that result in greater severity, chronicity, and impairment compared with either disorder alone. However, previous research has not systematically explored the potential effects of the psychotic subtyping of MDD and comorbid PTSD.

Does Comorbid Posttraumatic Stress Disorder Affect the Severity and Course of Psychotic Major Depressive Disorder?