English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Context Research is needed to find ways of improving physical activity after a lateral ankle sprain. Objective To investigate the effects of a prolonged rest period on lifelong activity after a surgically induced ankle sprain. Design Controlled laboratory study. Setting Research laboratory. Patients or Other Participants A total of 18 male CBA/J mice (age at surgery = 7 weeks). Main Outcome Measure(s) We transected the anterior talofibular ligament and calcaneofibular ligament of the right hindlimb. Each mouse was placed in a separate cage and randomized into 1 of 3 groups of 6 mice each. A running wheel was placed in each cage at 3 days, 7 days, or 14 days after surgery. Physical activity was measured daily. Daily duration (ie, time spent on the wheel), distance, and running speed were examined using analysis of variance (group × age) with repeated measures at 15-week periods to approximate the first 3 quartiles of the lifespan. Results From weeks 3 to 15 after surgery, we observed no differences in duration, distance, or running speed among groups (P &amp;gt; .05). From weeks 16 to 30, distance (F2,14 = 0.57, P = .041) and running speed (F2,14 = 0.93, P = .01) were greater in the 14-day group than in the 3- and 7-day groups. From weeks 31 to 45, duration (F2,14 = 0.74, P = .02), distance (F2,14 = 0.95, P = .009), and running speed (F2,14 = 1.05, P = .007) were greater in the 14-day group than in the 3- and 7-day groups. Conclusions Our findings suggest that the longer recovery period of 14 days can increase activity levels throughout the lifespan after a severe ankle sprain. Rest after an ankle injury is critical to restoring physical activity levels across the lifespan. Rest and time away from exercise after an ankle sprain may be necessary to restore physical activity to normal, uninjured levels.

A 14-Day Recovery and Physical Activity Levels After an Ankle Sprain in Mice