English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Hemoglobinopathies, common genetic disorders of hemoglobin, can be prevented by population screening and genetic counseling. Identification of these disorders is immensely important epidemiologically and aid in prevention of more serious hemoglobin disorders. Thalassemia is the commonest monogenic disorder in India, which belongs to the thalassemia belt of the world. The present study was undertaken to find out the characteristics of β-thalassemia trait and spectrum of this disorder among the rural population, screened under the hospital-based screening program in West Bengal, a state in eastern part of India. This study was carried out in school and college students, newly married couples and pregnant women after proper counseling in the rural areas of five southern districts of this state. Blood samples were tested by high-performance liquid chromatography. Total 1429 β-thalassemia traits were detected by random screening from this population. The mean value of HbA2 of the study population, having β-thalassemia trait is 4.9%. The prevalence (10.5%) of β-thalassemia trait in West Bengal is higher than other parts of the country. These data are likely to help us in future planning for screening programmes in rural areas of West Bengal, India.  血红蛋白病——常见的血红蛋白遗传疾病是可以通过人口筛查和遗传咨询的方法来预防的。鉴定此种疾病对于其传播性及预防其导致的更加严重的血红蛋白疾患有非常重大的意义。印度所处世界地中海贫血带地中海贫血在印度是最常见的单基因疾病。本研究的目的是通过医院筛查程序来研究印度西孟买邦农村人口有关β-地中海贫血症频谱和特征。该研究在印度南部的五个农村地区进行研究对象是接受过相关咨询后的在校生大学生新婚夫妇和孕妇。血液样本通过高效液相色谱法检测。总计1429例带有β-地中海贫血症特质的样本在这些人口中被随机筛查检测出。在该人口样本中患有β-地中海贫血症特质的HbA2的平均值为4.9%。在西孟加拉邦β-地中海贫血症特质的患病率为10.5%高于印度其他地区。这些数据有利于未来在印度西孟加拉邦农村地区的筛查项目。</p

thalassemia reports

The Prevalence and Characterization of β-Thalassemia Trait by Using High-Performance Liquid Chromatography among the Rural Population in West Bengal, India