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La enzima convertidora de angiotensina I (ECA2) a traves de Angiotensina (Ang)¬(1-9) mas que Ang-(1-7) contrarresta los efectos deletereos de ECA y Ang II. Se desconoce si Ang-(1-9) es efectiva en el tratamiento del remodelamiento cardiovascular (RMCV) hipertensivo, en ratas con polimorfismo del gen de la ECA.

Angiotensina-(1-9) disminuye el remodelamiento cardiovascular hipertensivo independiente de los niveles de ECA y de angiotensina II