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PALABRAS CLAVE: FIV, hiperestimulacion ovarica controlada, infertilidad SUMMARY Background: Controlled ovarian hyperstimulation (COH) is a main component of in-vitro fertilization (IVF) cycles. COH have been performed with daily exogenous gonadotropins administered, adding to treatment an additional component of stress. The appearance of a depot recombinant FSH (corifollitropin alfa) helps to reduce stress in patients undergoing IVF. No studies have shown differences in the number of retrieved oocytes or clinical pregnancy rates; however these studies have been funded by the pharmaceutical industry. Aims: To show the experience of Reproductive Medicine Unit Monteblanco with the use of corifollitropin alpha in autologous IVF cycles, in unselected patients. Methods: Our main outcome was the mean number of oocytes retrieved, and the proportion of oocytes in metaphase 2 in patients undergoing COH with corifollitropin alpha, daily recombinant FSH (rFSH), and a combination of rFSH and urinary gonadotropin. Results: We analyzed 727 IVF cycles: 270 cycles with corifollitropin alpha, 33 exclusive rFSH and 333 cycles with rFSH combination and urinary gonadotropins. We did not found any statistically significant difference in the

Experiencia de la Unidad de Medicina Reproductiva Clínica Monteblanco con el uso de corifollitropin alfa en ciclos de fecundación in vitro