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Functional foods (FF) are aimed to exert beneficial health effects. The isoflavones daidzein and genistein are bioactive phytoestrogens that may act as functional food ingredients. This study measured urinary excretion of these isoflavones contained in a powdered novel FF oriented to the elderly population, ready to consume as such or included into culinary preparations. The ingredients containing isoflavones were soybean flour, soybean protein (Glycine max L) and red clover extract (Trifolium pratense L). The study involved 30 volunteers of both sexes, 60 to 75 years old, who consumed 50 g of FF (n=16) or placebo food without isoflavones (n=14). The 24-hour urinary excretion of genistein and daidzein were determined before and after the intake of the mentioned foods by HPLC with diode array detector. The 24-h urinary concentration of genistein was 2.06 ± 1.41 ppm and the daidzein concentration was 8.80 ± 4.55 ppm. None of the individuals in the placebo group exhibited detectable amounts of isoflavones in urine. The study demonstrates that both phytoestrogens contained in the FF are bioavailable, first step to confirm their ability to exert bioactive effects. The study opens the possibility to verify the effects of both isoflavones to reduce risk factors of non transmissible chronical diseases. Key words: urinary excretion of isoflavones, functional foods, elderly, genistein, daidzein.Este trabajo fue recibido el 19 de Enero de 2009 y aceptado para ser publicado el 1 de Septiembre de 2009.zan como productos de la linea

EXCRECIÓN URINARIA DE ISOFLAVONAS EN ADULTOS MAYORES DE 65 AÑOS QUE CONSUMEN UN ALIMENTO FUNCIONAL