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129PREVENTION OF METHICILLIN RESISTANT Staphylococcus aureusNOSOCOMIAL INFECTION BY ELIMINATION OF CARRIERSMethicillin resistant Staphylococcus aureus (MRSA) nosocomial infectionis very prevalent and has important therapeutic and economic implications. Saureus carriers appear to play the major role on its pathogenesis, they can bepart of the medical team as well as patients. In this trial we studied S. aureusand MRSA carriers on the pediatric ICU’s medical team and patients. Themedical team had 28.8% (n: 13) of S. aureus carriage and 8.8% (n: 4) of MRSAon a nasal culture. On the other hand, patients were 33.5% (n: 43) positive atdifferent hospitalization periods for S. aureus and 16,4% (n: 21) for MRSA. Allof MRSA carriers were treated with nasal mupirocin. After the first treatmentcycle we found 100% eradication on the medical team group, and 85.7% onpatients, which increased to 100% after the second treatment cycle. The ICU’sMRSA nosocomial infection rate was significantly reduced during this study,from 5.19% (1998) to 0.57% (1999 first semester). We concluded that carriertreatment confers an important benefit, but it must be always associated togeneral measures for infection control, such a good hand scrubing.Key words: Methicillin resistant Staphylococcus aureus (MRSA); Carriertreatment; MRSA nosocomial infection prevention; Nasal mupirocin.EPIDEMIOLOGIA

Prevención de la infección intrahospitalaria por Staphylococcus aureus resistente a meticilina mediante el manejo de portadores