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Objective: To understand the characteristics of bacterial pathogens in children with respiratory tract infection. Methods: The clinical data of 15000 cases of children admitted to Children’s Hospital because of respiratory tract infection for consecutive 9 years from November 2005 to October 2014 were collected for retrospective analysis. Results: In 15000 cases of sputum specimens of children with respiratory tract infection, the first bacterial pathogens were Streptococcus pneumonia (12.79%). In different years, different seasons, different ages of children with bacterial, the differences of detection rate had statistical significance (P<0.01). The rate of 3 y old~ group was the highest, ≥ 5 y old group was the lowest, and the difference was statistically significant (χ2=92.83, P<0.001). In summer it was the highest, and autumn the lowest, the difference of which was statistically significant (χ2=22.18, P<0.001). The positive rate of sputum bacterial culture in children who didn’t receive antibiotics use before admission was higher than those who received antibacterial drugs (P<0.01). Conclusion: Streptococcus pneumoniae is the most common bacterial pathogens that cause respiratory tract infection of children, followed by Haemophilus influenzae and Moraxelle catarrhalis. The detection rate of bacterial pathogens varies in different years and seasons and children of different ages. The course of the disease before admission and the course of antibiotic use outside hospital had an effect on the positive detection rate of bacteria.

The characteristics of bacterial pathogens in 15000 cases of children with respiratory tract infection in Eastern area