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To determine the risk factors for the isolation rate of MRSA, we monitored hand disinfectant use, hand soap use, antimicrobial use density, nursing intensity and other characteristic of hospital from ˆscal 2010 to 2011 in 5 hospitals in Niigata. Statistically signiˆcant correlation was observed between the isolation rate of MRSA and nursing intensity (R=0.8982, p=0.04) in univariate analysis. Statistically marginally signiˆcant correlations and diŠerences was observed between the isolation rate of MRSA and all cephalosporin use (R=0.7606, p=0.14), and adoption of a notiˆcation system (63.0 vs 83.6, p=0.15). Nursing intensity was found to be a signiˆcant factor (R= 0.8982, p=0.04) by multiple regression analysis. These results suggest that hand hygiene quality and use of personal protective equipment was declining with increased nursing intensity, which resulted in increased isolation rate of MRSA. On the other hand, we considered that appropriate antibiotic use is important, because all cephalosporin use and adoption of a notiˆcation system was marginally signiˆcant factors. The results suggest that nursing intensity is one of the factors that aŠect the isolation rate of MRSA. Key wordsisolation rate of MRSA, nursing intensity, hand disinfectant use, antimicrobial use density, hand soap use

Risk Factor of Isolation Rate of MRSA: Evaluation of 5 Hospitals in Niigata