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Streptomycin (SM) is recommended by the World Health Organization (WHO) as a part of standard regimens for retreating multidrug-resistant tuberculosis (MDR-TB) cases. The incidence of MDR-TB in retreatment cases was 19% in Thailand. To date, information on SM resistance (SMR) gene mutations correlated to the SMR of Mycobacterium tuberculosis Thai isolates is limited. In this study, the mutations in rpsL , rrs , gidB , and whiB7 were investigated and their association to SMR and the lineage of M. tuberculosis were explored.

tuberculosis and respiratory diseases

Mutations in Streptomycin Resistance Genes and Their Relationship to Streptomycin Resistance and Lineage of<i>Mycobacterium tuberculosis</i>Thai Isolates

Mutations in Streptomycin Resistance Genes and Their Relationship to Streptomycin Resistance and Lineage ofMycobacterium tuberculosisThai Isolates