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too late for the disease to be cured. Yet others received an unnecessary cancer diagnosis that impacted their quality of life. This is the background doctors have to bear in mind in their encounters with the individual patient who wants a PSA test, a prostate biopsy or therapy. The test poses major challenges for doctors – partly because many healthy men request them, partly because we lack reliable criteria for who needs treatment once prostate cancer has been detected. On the basis of mathematical models, it has been estimated that PSA screening contributes to 45 – 70 % of the observed reduction in deaths specifically attributable to prostate cancer, but that 23 – 42 % of the cases of prostate cancer detected by PSA testing represent overdiagnosis (1). So far, PSA screening has not been shown to bring about a reduction in total mortality.

Overforbruk av PSA-test hos friske menn