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The objective of this study was to evaluate the effectiveness of reusing a controlled internal drug release (CIDR) device for up to three times in the reproductive performance of dairy goats raised in the semi-arid zone of northeastern Brazil. Forty-five goats were allocated into three hormone treatments, as follows: CIDR1x, treated with new CIDR during nine days. Two days prior to device removal, injections of 75 µg d-cloprostenol and 300 IU equine chorionic gonadotropin (eCG) were administrated. For the other treatments, the same hormone protocol was used, differing only by the use of the same CIDR for a second time in CIDR2x and for a third time in CIDR3x. The interval from device removal to the onset of estrus (13.3 ± 1.1h vs. 13.8 ± 2.6h vs. 13.3 ± 1.4h), as well as estrus duration (33.6 ± 7.3h vs. 29.6 ± 3.2h vs. 32.8 ± 4.5h), did not differ (p > 0.05) among groups CIDR1x, CIDR2x and CIDR3x, respectively. All synchronized females were found to be in estrus. The overall fertility and prolificacy after artificial insemination were 82.2% and 1.9 kids, respectively, without significant difference (p > 0.05) among treatments. The use of the same CIDR for up to three times was effective using 9-day estrus synchronization protocols in dairy goats. The objective of this study was to evaluate the effectiveness of reusing a controlled internal drug release (CIDR) device for up to three times in the reproductive performance of dairy goats raised in the semi-arid zone of northeastern Brazil. Forty-five goats were allocated into three hormone treatments, as follows: CIDR1x, treated with new CIDR during nine days. Two days prior to device removal, injections of 75 µg d-cloprostenol and 300 IU equine chorionic gonadotropin (eCG) were administrated. For the other treatments, the same hormone protocol was used, differing only by the use of the same CIDR for a second time in CIDR2x and for a third time in CIDR3x. The interval from device removal to the onset of estrus (13.3 ± 1.1h vs. 13.8 ± 2.6h vs. 13.3 ± 1.4h), as well as estrus duration (33.6 ± 7.3h vs. 29.6 ± 3.2h vs. 32.8 ± 4.5h), did not differ (p > 0.05) among groups CIDR1x, CIDR2x and CIDR3x, respectively. All synchronized females were found to be in estrus. The overall fertility and prolificacy after artificial insemination were 82.2% and 1.9 kids, respectively, without significant difference (p > 0.05) among treatments. The use of the same CIDR for up to three times was effective using 9-day estrus synchronization protocols in dairy goats

Using the same CIDR up to three times for estrus synchronization and artificial insemination in dairy goats