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Matrix metalloproteinase (MMP)-9 is excessively expressed in frail region of atherosclerotic plaque and released in circulation following plaque rupture. High MMP-9 level associated with severity of occluded thrombus and subsequent myocardial infarction. MMP-9 (-1562C&gt;T) polymorphism associated with acute myocardial infarction, however conflicting data present regarding impact of MMP-9 (-1562C&gt;T) polymorphism on circulating MMP-9 level in acute myocardial infarction with ST-elevation (STEMI), clinical entity represents totally occluded coronary thrombus.

cardiology research

Association Between High Serum Matrix Metalloproteinase-9 and MMP-9 (-1562C&gt;T) Polymorphism in Patients With ST-Elevation Acute Myocardial Infarction