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This study compared the effect of experimental polymer-based desensitizers with NaF and oxalic acid (OA) for preventing root demineralization via observation using micro-CT. Bovine root dentin surfaces were treated with coating materials: no treatment; MS0(+) (MS Coat One ® ); MS3000(+) (MS Coat ® ); MS0(-); MS3000(-); MS7000(+/-); fluoride gel (NaF9000). MS; MS polymer, 0-7000; NaF concentrations, (+/-); OA. The specimens were scanned using micro-CT before and after demineralization (pH4.5, 10 h). Following this, the mean mineral loss (ML) after demineralization was calculated, and the specimens were observed under a scanning electron microscope (SEM). The ML values of MS3000(+), MS7000(-), MS7000(+) and NaF9000 were significantly lower than the other groups (p&lt;0.05). Under an SEM, a membrane structure was observed to have formed on the dentin surface in the presence of the MS, fluoride, and OA. The experimental polymer-based desensitizer with oxalic acid and a high concentration of fluoride is effective for preventing root demineralization.

Preventive effect of experimental polymer-based desensitizers with NaF on demineralization of root dentin —observed using micro-CT