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【Purpose】 Systolic and diastolic blood pressure (SB P and DBP) by the cuff measurement of the upper arm have been the markers of the effectveness of the depressants. However, it has been reported SBP and DBP do not reflect the blood pressure of the as cending aorta, which is the true load of the heart1,2). More reliable and usable examinations than SBP & D BP are needed. These mehods should be easy and noninvasive, and reflect the aortic pressure or peri pheral circulation.The candidates for these methods are (1) late systolic shoulder of the peripheral artery. (2)parameter of the cardiac contractility fromthe imp edance cardiography. In order to discuss the validity of these methods, we studied the pharmacological effects of vasodilator, Nifedipine. 【Methods】 Subjects were 6 healthy normotensive

Usefulness of Impedance Cardiography and Pulse Study for the Evaluation of the Pharmacological Action of the Depressants.