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Regenerated axons grew earlier in grafts administrated with MCB than in control grafts. The density of regenerated myelinated fibers was higher in the grafts with MCB than in control. Diameters of myelinated fibers became larger in grafts with MCB than in control at early postoperative stage. There was no differences in regenerated axons at the late stage, more than six weeks, between in grafts administrated with MCB and in control grafts. We suggest that MCB will make an activation of Schwann cell and help a smooth regeneration of axons.

Effects of Methylcobalamin (MCB) on the Experimental Free Nerve Graft