English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

In the past decade, metal catalyzed or promoted C-H bond activation appears as an attractive alternative to classical cross-coupling reaction. Although the studies of this methodology have grown considerably, applications in total synthesis of natural products remain rare. This short review will focus on the use of the metal catalyzed or promoted C-H bond functionalization for the total synthesis of rhazinilam and congeners and demonstrate the usefulness and the efficiency of this approach.

Three different approaches to C-H bond functionalization in the synthesis of antitumor alkaloids rhazinilam, rhazinal and rhazinicine