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A facile synthesis of novel symmetrical and unsymmetrical bis-[spiro(indole-indazolylthiazolidine)-2,4′-diones] 5a-f has been achieved via hitherto unknown bis-Schiff bases 3a-f, which in turn have been prepared from the earlier reported (1H-indol-2,3-dione)-1,1′-(1,6hexanediyl)bis 1a-c and 5-substituted-1-[6-(2,3-dioxoindolyl)hexyl]-1H-indol-2,3-diones 1d-f.

Synthesis of novel symmetrical and unsymmetrical bis-spiro[indole-indazolyl-thiazolidine]-2,4'-diones