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One pot synthesis of quinazolin-1-one derivatives has been achieved from 2aminobenzothaizoles, 1,3-cyclohexanedione and aromatic aldehydes in presence of anhydrous zinc chloride catalyst. This methodology provides several advantages simple & mild reaction conditions and excellent yield.

Anhydrous zinc chloride: an efficient catalyst for one pot synthesis of 2,3,4,12-tetrahydrobenzothiazolo[2,3b]quinazolin-1-ones