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Synthesis of 3-{naphtho(2,1-b)furan-2-ylcarbonyl}-3H-1,3,4-benzotriazepine 6 was reported. The conversion of 3 into various substituted derivatives of schiff bases by reacting with substituted 2-aminobenzaldehyde 4, which intern cyclise in presence of triethyl ortho formate to produce the title compounds. The structures of all the newly synthesized compounds have been established by 1 H NMR, IR, Mass spectra and elemental analysis. The selected compounds have been screened for antibacterial and antifungal activities.

Microwave assisted synthesis of naphtho[2,1-b]furan-1, 3, 4-benzotriazepines: a potent antimicrobial agent