English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Women with myocardial ischemia without obstructive coronary artery disease (CAD) often have microvascular coronary dysfunction (MCD). Traditional cardiac risk factors (RFs) contribute modestly to MCD detected by invasive coronary reactivity testing (CRT). Cardiac magnetic resonance imaging (CMRI) is an emerging noninvasive technique used to evaluate MCD. We evaluated RFs related to CMRI myocardial perfusion in women with MCD. 53 women with CRT confirmed MCD underwent adenosine stress and rest CMRI (1.5 Tesla). The myocardial perfusion reserve index (MPRI) was calculated (Pie Medical) with lower MPRI meaning less perfusion reserve. Relationships between RFs and MPRI were examined. The mean age was 54±10 years with a mean body mass index (BMI) of 26.2±4.2. The mean MPRI was 1.63±0.39. Hypertension, dyslipidemia, elevated BMI, and post-menopausal status were inversely related to MPRI, while ever smoking, age, family history of CAD, history of irregular menses, and history of menopausal hormone therapy (MHT) or oral contraceptive (OC) use were not. Dyslipidemia and BMI remained significant independent predictors of MPRI. Regression modeling demonstrated that the RFs of dyslipidemia, obesity, hypertension, family history of CAD, and history of irregular menses explained 27% of the observed MCD variance.

Cardiac risk factors and myocardial perfusion reserve in women with microvascular coronary dysfunction.