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This experiment was performed as a part of the series of the electron microscopic studies on vestibular apparatus.(1) The cells of ampullae of the labyrinth which were damaged with Viomycin in various doses were revealed electron microscopically.(2) The cell surface and the apical cytoplasm of ampullae of the labyrinth were damaged.(3) The dense body and multivesicular body extremely resembling lysosome were observed.(4) There was evidence morphologically that the onset of cell damage by Viomycin seemed to begin at the cell surface such as effect of Strepto. mycin or Kanamycin.

ELECTRON MICROSCOPIC OBSERVATION ON THE EFFECT OF ACTINOMYCETE STREPTOMYCES PUNICENS (VIOMYCIN) IN THE VESTIBULAR APPARATUS