Open AccessProtein and Calorie Restriction Contribute Additively to Protection from Renal Ischemia Reperfusion Injury Partly via Leptin Reduction in Male Mice
Author(s) -
Lauren Robertson,
J. Humberto Treviño-Villarreal,
Pedro Mejia,
Yohann Grondin,
Eylul Harputlugil,
Christopher Hine,
Dorathy Vargas,
Hanqiao Zheng,
C. Keith Ozaki,
Bruce S. Kristal,
Stephen J. Simpson,
James R. Mitchell
Publication year - 2015
Publication title -
journal of nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.463
H-Index - 265
eISSN - 1541-6100
pISSN - 0022-3166
DOI - 10.3945/jn.114.199380
Subject(s) - leptin , ampk , calorie restriction , adiponectin , medicine , endocrinology , protein kinase a , mtorc1 , biology , calorie , hormone , signal transduction , kinase , biochemistry , insulin , insulin resistance , obesity , pi3k/akt/mtor pathway
Short-term dietary restriction (DR) without malnutrition preconditions against surgical stress in rodents; however, the nutritional basis and underlying nutrient/energy-sensing pathways remain poorly understood.
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