Open AccessEffect of dietary phosphate intake on the circadian rhythm of serum phosphate concentrations in chronic kidney disease: a crossover study
Author(s) -
Joachim H. Ix,
Cheryl A.M. Anderson,
Gerard Smits,
Martha S. Persky,
Geoffrey A. Block
Publication year - 2014
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.3945/ajcn.114.085498
Subject(s) - phosphate , circadian rhythm , endocrinology , medicine , kidney disease , morning , crossover study , chemistry , phosphate binder , hyperphosphatemia , zoology , biology , biochemistry , placebo , pathology , alternative medicine
Previous trials of binders in chronic kidney disease (CKD) stages 3-5 have shown only modest changes in serum phosphate but evaluated morning phosphate. It is unknown whether a circadian pattern of phosphate concentrations exists in CKD and is modifiable by dietary manipulation.
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