Open AccessA comparison of zinc metabolism, inflammation, and disease severity in critically ill infected and noninfected adults early after intensive care unit admission
Author(s) -
Beth Y. Besecker,
Matthew C. Exline,
Jennifer L. Hollyfield,
Gary Phillips,
Robert A. DiSilvestro,
Mark D. Wewers,
Daren L. Knoell
Publication year - 2011
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.3945/ajcn.110.008417
Subject(s) - critically ill , intensive care unit , medicine , intensive care medicine , systemic inflammation , critical illness , inflammation , disease , severity of illness , intensive care
Zinc deficiency is a cause of immune dysfunction and infection. Previous human studies have shown that the activation of the acute phase response alters zinc metabolism. Whether the alteration in zinc metabolism is predictive of disease severity in the setting of critical illness is unclear.
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