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1. Specht M, Brellochs J, Frick V, et al. (2010) Storage of renewable energy in the natural gas grid. Erdoel, Erdgas, Kohle 126: 342-345. 2. Thauer RK, Kaster AK, Goenrich M, et al. (2010) Hydrogenases from methanogenic archaea, nickel, a novel cofactor, and H2 storage. Annu Rev Biochem 79: 507-536. 3. Liu Y, Whitman WB (2008) Metabolic, phylogenetic, and ecological diversity of the methanogenic archaea. Ann N Y Acad Sci 1125: 171-189. 4. Kaster AK, Goenrich M, Seedorf H, et al. (2011) More than 200 genes required for methane formation from H2 and CO2 and energy conservation are present in Methanothermobacter marburgensis and Methanothermobacter thermautotrophicus. Archaea ID 973848: 1-23. 5. Seifert AH, Rittmann S, Herwig C (2014) Analysis of process related factors to increase volumetric productivity and quality of biomethane with Methanothermobacter marburgensis Appl Energ 132: 155-162. 6. Bernacchi S, Weissgram M, Wukovits W, et al. 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Bonacker LG, Baudner S, Thauer RK (1992) Differential expression of the two methyl-coenzyme M reductases in Methanobacterium thermoautotrophicum as determined immunochemically via isoenzyme-specific antisera. Eur J Biochem 206: 87-92. 27. Bonacker LG, Baudner S, Moerschel E, et al. (1993) Properties of the two isoenzymes of methyl-coenzyme M reductase in Methanobacterium thermoautotrophicum. Eur J Biochem 217:587-595. 28. Hallenbeck PC, Ghosh D (2009) Advances in fermentative biohydrogen production: the way forward? Trends Biotechnol 27: 287-297. 29. Wang J, Wan W (2008) Optimization of fermentative hydrogen production process by response surface methodology. Int J Hydrogen Energy 33: 6976-6984. 30. Rittmann S, Herwig C (2012) A comprehensive and quantitative review of dark fermentative biohydrogen production. Microbial Cell Factories 11:115. 31. Spadiut O, Rittmann S, Dietzsch C, et al. (2013) Dynamic process conditions in bioprocess development. Eng Life Sci 13: 88-101. 32. 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aims bioengineering

Experimental methods for screening parameters influencing the growth to product yield (Y&lt;sub&gt;(x/CH4)&lt;/sub&gt;) of a biological methane production (BMP) process performed with &lt;em&gt;Methanothermobacter marburgensis&lt;/em&gt;