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A series of 20 patients who underwent surgical operation at our hospital from August 1998 to September 1999 were applied to use the ozonized olive oil for their intractable fistulae or wounds. There were three cases of intractable fistula after operation for inguinal hernia, including one case of intractable fistula with infected mesh; four cases of fistula after operation for acute appendicitis with peritonitis; five cases of intractable wound after operation for infected epidermal cyst; one case of fistula after incision of infected urachal cyst; three cases of fistula after incision and drainage for perianal abscess, including one case for periviorectal abscess; three cases of fistula after incision and drainage for infected pilonidal sinus; and the remaining one case of lower limb ulceration after sunburn. This ozonized olive oil was fully effective in all 19 cases except for one case of pilonidal sinus. No adverse side effects were observed in the administration of the ozonized olive oil. The main active component of the ozonized olive oil has been found to be triozonide. It was fully effective for a discharge of pus and a formation of granuratlon.

THERAPEUTIC EFFECTS OF OZONIZED OLIVE OIL IN THE TREATMENT OF INTRACTABLE FISTULA AND WOUND AFTER SURGICAL OPERATION