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IVSI-110 (G&gt;A), IVSI-6 (T&gt;C), IVSII-1 (G&gt;A), IVSII-745 (C&gt;G), IVSI-1 (G&gt;A), and HbS are mutations covering 76% of all the β-globin mutations in the Turkish population. In this study, our aim is to develop a reliable, fast, real-time kit for these mutations using the TaqMan probe method.

Development of a new real-time PCR screening kit for HbS and common beta-thalassemia mutations observed in Turkey