Open AccessSynthesis of some ketones via nano-nickel oxide catalyzed acylation of arylzinc reagents; strategy involving the use of mixed (methyl)(aryl)zincs
Author(s) -
Özgen Ömür Pekel,
Ender Erdık,
Melike Kalkan
Publication year - 2018
Publication title -
turkish journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.239
H-Index - 46
eISSN - 1303-6130
pISSN - 1300-0527
DOI - 10.3906/kim-1712-28
Subject(s) - chemistry , catalysis , acylation , aryl , denticity , non blocking i/o , phosphine , halide , reagent , nickel oxide , ligand (biochemistry) , nickel , medicinal chemistry , organic chemistry , polymer chemistry , combinatorial chemistry , biochemistry , alkyl , receptor , crystal structure
Nano-NiO catalyzed acylation of mixed (methyl)(aryl)zincs with aromatic acyl halides in THF at room temperature provides a new facile route for aryl–aroyl coupling. Among NiCl2 .L2 and NiCl2 .L (L = monodentate and bidentate phosphine ligand) catalysts, the lower catalyst loading of NiCl2 (dppf) may seem attractive; however, nano-NiO, being the lowest cost catalyst, is more favorable for aroylation of (methyl)(aryl)zincs. This procedure also provides a supplement to Cu and Pd catalyzed acylation of diorganozincs.
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