Open AccessNovel $N$-acyl/aroyl-2-(5-phenyl-2$H$-tetrazol-2-yl)acetohydrazides: synthesis and characterization
Author(s) -
Aamer Saeed,
Majid Hussain,
Muhammad Qasim
Publication year - 2014
Publication title -
turkish journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.239
H-Index - 46
eISSN - 1303-6130
pISSN - 1300-0527
DOI - 10.3906/kim-1307-13
Subject(s) - chemistry , tetrazole , elemental analysis , proton nmr , medicinal chemistry , fourier transform infrared spectroscopy , stereochemistry , organic chemistry , quantum mechanics , physics
A number of novel N-acyl/aroyl-2-(5-phenyl-2H-tetrazol-2-yl)acetohydrazides (4a--j) of biological interest were efficiently synthesized by treating 2-(5-phenyl-2H-tetrazole-2-yl)acetohydrazide (3) with a variety of aroyl/hetero- cyclyl or alkanoyl chlorides. FTIR, 1H NMR, 13C NMR, GC-MS, and elemental analyses data confirmed the structures assigned to the newly synthesized compounds.
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