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Liver cirrhosis is a diffuse hepatic fibrosis, and nodule formation. The transforming growth factor-beta 1 (TGF-beta 1) and interleukin-10 (IL-10) are very important cytokines in hepatic fibrogenesis. The aim of this study was to examine the relationship between the changes of the serum cytokines and morphological changes following common bile duct ligation in experimental rats.

Changes in Serum Cytokine Concentration: A Morphological Study of Liver Cirrhosis Induced by Common Bile Duct Ligation in Rats