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TGF-beta is known as a cell growth inhibitory factor to suppress almost all cells, including the epithelial cell. Unlike normal cells, cancer cells are not affected by TGF-beta growth inhibitory action and the lack of TGF-beta receptor expression or mutation is being reported as its mechanism, which is rarely studied in Korea. Therefore, we investigated this study to clarify the role of TGF-beta I and TGF-beta II receptors in gastric cancer.

Role of TGF - β1 and TGF - β Type 2 Receptor in Gastric Cancer