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The significance of the coccoid forms of H. pylori is still controversial and the questions of whether these forms are viable and infective or degenerative are still open. We induced conversion from rod to coccoid forms and studied morphological changes and antigenic evolutions during this conversion and, thereby, elucidated the viability of coccoid forms.

Changes in the Evolution of the Antigenic Profiles and Morphology during Coccoid Conversion of Helicobacter pylori