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Intercellular adhesion molecule-1 (ICAM-1), a 80-110 kD glycoprotein, has been found to be a ligand for the lymphocyte function associated antigen-1 (LFA-1) molecule and has important roles in inflammatory and immune mediated mechanisms. ICAM-1 is expressed on thyroid follicular cells of patients with Hashimoto disease and cultured thyroid monolayer cells derived from the thyroid surgical specimen. In addition to the expression of ICAM-1 on the surface of cells, soluble variants of several adhesion molecules have been reported.

the korean journal of internal medicine/korean journal of internal medicine

Circulating Intercellular Adhesion Molecule-1ICAM-1 in Sera of Patients with Graves` Disease and Hashimoto Disease - The Levels of Circulating ICAM-1 Are Positively Correlates with Serum Titers of Antithyroperoxidase Antibody -