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The study by Ying, et al (1) of ischemic stroke risk in systemic sclerosis (SSc) reported increased prevalence (15.3 vs 12.2 per thousand in the control cohort) and delineated a series of likely predisposing comorbidities. There is an additional consideration, also amenable to risk adjustment: such events are also characteristic of the effect of antiphospholipid antibodies (aPL)(2).

Foundation for Stroke in Systemic Sclerosis: A Clarion Call for Proactive Assessment?