English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

: Bacterialmeningitis   is an acute purulent infection of the meninges. There are significant differences in the etiological spectrum, clinical course and outcome of bacterialmeningitis   in the age groups, and their recognition is important for early diagnosis and adequate therapy.Aim : The study aims to determine the differences in the etiology and clinical presentation of bacterialmeningitis   between children and adults.Materials and methods : The study included 90 patients (25 children and 65 adults) with bacterial neuroinfection admitted to St George University Hospital, Plovdiv between January 1, 2016 and September 31, 2019. We applied epidemiological and clinical analysis, microbiological and statistical methods.Results : In adults, the most common etiological agent was    Streptococcus   pneumoniae    (20%), followed by    Staphylococcus    spp. (18.5%),    Listeria   monocytogenes    (12.3%),    Streptococcus    spp. (3.1%),    Haemophilus   influenzae    (3.1%),    Klebsiella   pneumoniae    (1.5%), and    Mycobacterium   tuberculosis    (1.5%). The etiological structure in children was different:    Neisseria   meningitidis    (20%),    Streptococcus   pneumoniae    (16%),    Klebsiella   pneumoniae    (8%),    Enterococcus   faecium    (8%),    Streptococcus   salivarius    (4%), and    Mycobacterium   tuberculosis    (4%). In 40% of the cases, both children and adults, the causative agent was not identified.Conclusions : Regarding the clinical presentation, a statistical significance between the age groups was found with headache and alterations in consciousness, more commonly seen in adults, while vomiting, ear pain was more common in children ( p &lt;0.05). Concomitant otitis, sinusitis, pneumonia, and sepsis were often observed. The mortality rate was much higher in adults (43%) when compared with children (8%).

A comparative study between children and adults with bacterial neuroinfections