English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

The inhibitor of DNA binding (ID)-1 protein, an inhibitor of basic helix-loop-helix transcription factors, has been found to be involved in multiple cellular functions. In the present study, ID-1 histoscores and mRNA levels were both significantly (p&lt;0.05) increased in uterine endometrial cancers according to clinical stage, histological grade and depth of myometrial invasion. Furthermore, the 60-month survival rate of the 25 patients with high ID-1 was poor (52%), while that of the other 25 patients with low ID-1 was significantly higher (80%) (p&lt;0.05). ID-1 histoscores and mRNA levels significantly (p&lt;0.0001) correlated with microvessel counts in uterine endometrial cancers. Therefore, ID-1 acts on tumor advancement via angiogenic activity and can be considered a candidate prognostic indicator in uterine endometrial cancers.

Role of inhibitor of DNA binding-1 protein is related to angiogenesis in the tumor advancement of uterine endometrial cancers