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In order to identify factors that may contribute to osteoporosis, a cross sectional study of Japanese females over the age of 50 was conducted at 13 health centers in Ibaraki Prefecture in the period from December 1992 through March 1993 . Based on the criteria employed by the Orimo Research Group at the Ministy of Public Health and Welfare, 136 subjects were classified as having osteoporosis. Analysis of these data revealed several statistically significant differences between subjects with osteoporosis and the control group (n=680) . Some factors potentially thought to be associated with osteoporosis were not found to be statistically significant. Exercise was less frequent among those with osteoporosis in the group of subjects aged 60-69. The calcium intake of those subjects 70 and above was also significantly less for those with osteoporosis. Additionally, menopause occurred earlier among those with osteoporosis for subjects aged 50-69 . However, there was no significant difference between the control group and the group with osteoporosis in the age of menarche, nor in the rate of childbirth . Nor were statistically significant differences found between the groups in alcohol drinking, smoking or sun bathing. With the exception of serum P for those aged 50-59, there were also no significant differences between the groups in serum Ca, ALP or albumin. Regarding health status, the health of subjects aged from 50-59 with osteoporosis was significantly worse. For subjects aged 60-69, the rate of bone fractures was higher for subjects with osteoporosis, though there were no significant differences between the two groups in fall related injuries occurring in the previous year.

A Study of Osteoporosis Among Females Aged 50 Years and Over Using Mass Screening Data.