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Both IL28B gene polymorphisms and serum levels of interleukin (IL)-10, IL-12p40 and IL-18 have been reported to affect the outcome of natural and pegylated interferon and ribavirin-treated HCV infection.

Serum Interleukin (IL)-10 and IL-12 Levels andIl28BGene Polymorphisms: Pretreatment Prediction of Treatment Failure in Chronic Hepatitis C