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We present a new investigation of the dependence of H2O maser detection ratesand properties on the mid-IR AGN luminosity, L_AGN, and the obscuring columndensity, N_H, based on mid-IR and hard X-ray photometry. Based on spectralenergy distribution fitting that allows for decomposition of the black holeaccretion and star-formation components in the mid-infrared, we show that themegamaser (disk maser) detection rate increases sharply for galaxies with 12micron AGN luminosity L^{AGN}_{12 micron} greater than 10^42 erg/s, from~<3%(~<2%) to ~12%(~5%). By using the ratio of the observed X-ray to mid-IR AGNluminosity as an indicator of N_H, we also find that the megamaser (disk maser)detection rates are boosted to 15%(7%) and 20%(9%) for galaxies with N_H >=10^23 cm^{-2} and N_H >= 10^{24} cm^{-2}, respectively. Combining these columndensity cuts with a constraint for high L^{AGN}_{12 micron} (>=10^42 erg/s)predicts further increases in the megamaser (disk maser) detection rates to19%(8%) and 27%(14%), revealing unprecedented potential boosts of the megamaserand disk maser detection rates by a factor of 7-15 relative to the currentrates, depending on the chosen sample selection criteria. A noteworthy aspectof these new predictions is that the completeness rates are only compromisedmildly, with the rates remaining at the level of ~95%(~50%) for sources withN_H >= 10^{23} cm^{-2} (N_H >= 10^24 cm^-2). Applying these selection methodsto the current X-ray AGN surveys predicts the detection of >~15 new megamaserdisks.

A More Efficient Search for H2O Megamaser Galaxies : The Power of the X-ray and Mid-infrared Photometry