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Clarifying the biodegradation mechanism of lignin is not only the primary key scientific issue which needs to be elucidated, but also the urgent theoretical basis for solving the practical application problems. The study of lignin degradation mechanism needs to follow the change of substrate and start from enzyme itself. It’s a lot of work to figure out these problems, and some trace proteins are easily overlooked. Proteomics is an effective means to explore protein action patterns, functional mechanisms, and regulation control as well as interrelationship within the EXTRACELLULAR DIFFERENTIAL PROTEOME ANALYSIS OF SUBSTRATES OF DIFFERENT LIGNIN MODEL COMPOUNDS DEGRADED BY ASPERGILLUS FUMIGATUS G-13