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Aim: Pain is the major problem early postoperative period after perianal operations. In this study, we aimed to evaluate the effect of adding 50 μg or 100 μg of morphine on intrathecal 5 mg hyperbaric bupivacaine on postoperative analgesia before anal surgery. Material and Method: A total of 60 patients divided into 3 groups, including 20 patients in each group, were included for the study; Group 1: 5 mg 0.5% heavy bupivacaine (HB), Group 2: 5 mg 0.5% HB and 50 μg Morphine, Group 3: 5 mg 0.5% HB and 100 μg Morphine was intrathecally administered. Intraoperative and postoperative hemodynamics, time to urination and first analgesia requirement, perioperative and postoperative side effects were recorded Results: The time to first analgesic need in Group 1 (305.40 ± 143.86) was statistically significantly lower than Group 2 (435.50 ± 171.70) and Group 3 (435.50 ± 156.08) was determined (p=0.015). No significant difference was found between urinary retention (p>0.05). It was determined that the postoperative nausea and vomiting percentages (25.0%) in Group 3 were statistically significantly higher than Group 2 (5.0%) and Group 1 (0.0%) (p<0.05). Conclusions: The use of 50 μg of intrathecal morphine in patients undergoing perianal surgery in saddle block anesthesia has the expected effect on postoperative analgesia and it is considered appropriate to be preferred in perianal surgery because it causes minimal adverse side effects.

The effect of adding morphine to intratecal bupivacaine on postoperative analgesia in patients with perianal surgery