English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Review question / Objective: Currently, pars plana vitrectomy (PPV) with ILM peeling is the gold standard treatment for full thickness macular hole (FTMH). Despite of the high macular hole closure rate, a refractory FTMH may occur. The next step for a recurrent or persistent MH is usually repeat PPV with extended ILM peeling. This is not always an option especially with high myopia patients or those who had already undergone an aggressive ILM peeling at initial surgery. A variety of novel techniques have been developed to address this issue, among which human amniotic membrane seems to be a promising adjuvant. However, there are still uncertainties regarding the integration and the long-term effects of of the graft. Information sources: PubMed, Embase, Web of science, Cochrane library, Wanfang Data Knowledge Service Platform, China National Knowledge Infrastructure databases, sinomed (CBM), VIP database, Clinical Trails.gov and Chinese Clinical Trail Registry.

Human amniotic membrane graft for refractory macular hole: a single-arm meta analysis and systematic review