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Review question / Objective: An umbrella review of systematic reviews of the use of β-hydroxy-β-methyl butyrate (HMB) supplementation in promoting skeletal muscle mass and function in aging and clinical practice. Condition being studied: Muscle mass (and various proxies thereof), strength, and physical function.  Information sources: Pubmed, Web of Science, Embase.

An umbrella review of systematic reviews of β-hydroxy-β-methyl butyrate (HMB) supplementation in promoting skeletal muscle mass and function in aging and clinical practice