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Drinking was elicited by microinjection of angiotensin-II throughout the medial regions of the brain of the cat. At many of these same sites, a hypertonic sodium chloride solution also elicited drinking, as did a 5-ion solution and serotonin, on occasion. However, these other solutions were almost invariably effective only at angiotensin-drinking sites. Diffusion via the ventricular or circulatory system may account for some of these data.

Angiotensin-induced drinking in the cat: A neuroanatomical analysis