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The influences of central applications of adrenergic and cholinergic stimulating and blocking agents to the cat thalamus on successive visual discrimination performance were investigated. Applications of both noradrenaline and the adrenergic blocking agent ethobutamoxane improved discrimination performance by reducing nonreinforced responding. Conversely, injections of both the cholinergic stimulator and blocker disrupted visual discrimination. Carbachol reduced responses to the discriminative stimulus without affecting nonreinforced response rate, and atropine sulfate increased nonreinforced responses without changing the rate of reinforced responding.

Injections of neurohumors in the cat thalamus and visual discrimination performance