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Rats poisoned either immediately or 4 h after consuming one novel solution were subsequently tested with either a water vs. the conditioned novel solution choice or with a water vs. a second unconditioned novel solution choice. The results showed that: (1) there was a significant avoidance of both solutions by the immediately poisoned groups compared to their respective controls, and (2) there was a clear avoidance of the unconditioned novel solution and a marginal avoidance of the conditioned novel solution by the 4-h poisoned groups compared to their respective controls. The absence of a generalization decrement indicates that associative mechanisms such as stimulus generalization cannot adequately account for these results. An alternative explanation, based on the interaction of associative mechanisms with the habituation and sensitization of neophobia is proposed.

Absence of a generalization decrement in the poison-induced avoidance of interoceptive stimuli in the rat