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I compared the randomization/permutation test and the F test for a two-cell comparative experiment. I varied (1) the number of observations per cell, (2) the size of the treatment effect, (3) the shape of the underlying distribution of error and, (4) for cases with skewed error, whether or not the skew was correlated with the treatment. With normal error, there was little difference between the tests. When error was skewed, by contrast, the randomization test was more sensitive than the F test, and if the amount of skew was correlated with the treatment, the advantage for the randomization test was both large and positively correlated with the treatment. I conclude that, because the randomization test was never less powerful than the F test, it should replace the F test in routine work.

A comparison of the randomization test with theF test when error is skewed