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Meniere's disease was diagnosed in 182 cases or 5.8% of 3, 150 patients who had consulted the Neuro-otological clinic in Kitasato University Hospital between 1990 and 1995. Females were dominant comprising 70% of 151 patients. Patient age at the onset of the disease ranged from the third to fifth decade. Patients were treated by medication and Portmann's sac procedure was done in 12 cases.Initial symptoms and prognosis of vertigo and hearing impairments were investigated in 28 selected patients who were successfully followed over a long term. Tinnitus and/or deafness started before the first vertigo attack in 61% of the 28 patients. The left ear was more frequently affected than the right and both ears were affected in 12.7%. The interval between the first and second attacks of vertigo was more than one year in 21.4%. More than one year passed since the last vertigo attack in 60.7%. However, an interval of more than one year during the long term course was also observed in the same percentage. Average of hearing levels did not change or had worsened at the end of long term follow-up in all 28 cases.

Vertigo and Cochlear Signs at the Early Stage and Prognosis in Meniere's Disease.